Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.55 |
| ▸ | PREP | P48147 | 5/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434440 | 1.00 | ACE2 (0.55) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL13434443 | 1.00 | ACE2 (0.55) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3070684 | 0.88 | PREP (0.53) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3070690 | 0.88 | PREP (0.53) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3070688 | 0.88 | PREP (0.53) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL16789713 | 0.84 | PREP (0.49) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL10310512 | 0.82 | PREP (0.56) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3011829 | 0.82 | PREP (0.56) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3070355 | 0.81 | PDE4B (0.49) | ACE2PREPCTRB1NPSR1TSHR | |
| SCHEMBL3070354 | 0.81 | PDE4B (0.49) | ACE2PREPCTRB1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |