Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953837 | 0.89 | ABL1 (0.41) | ABL1 | |
| SCHEMBL12140470 | 0.88 | ABL1 (0.38) | ABL1 | |
| SCHEMBL12140672 | 0.83 | ABL1 (0.40) | ABL1 | |
| SCHEMBL12229502 | 0.83 | ABL1 (0.40) | ABL1 | |
| SCHEMBL8997556 | 0.82 | ABL1 (0.39) | ABL1 | |
| SCHEMBL13788311 | 0.82 | ABL1 (0.40) | ABL1 | |
| SCHEMBL12140468 | 0.82 | ABL1 (0.35) | ABL1 | |
| SCHEMBL9068458 | 0.81 | ABL1 (0.43) | ABL1 | |
| SCHEMBL9068596 | 0.81 | ABL1 (0.39) | ABL1 | |
| SCHEMBL13953884 | 0.81 | ABL1 (0.38) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618974-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-17 | — | — | US | disclosed |
| US-7495014-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |