Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953890 | 0.92 | ABL1 (0.54) | ABL1 | |
| SCHEMBL13712078 | 0.89 | ABL1 (0.56) | ABL1 | |
| SCHEMBL9068495 | 0.82 | ABL1 (0.58) | ABL1 | |
| SCHEMBL8997588 | 0.79 | ABL1 (0.57) | ABL1 | |
| SCHEMBL1358290 | 0.78 | ABL1 (0.60) | ABL1 | |
| SCHEMBL8997225 | 0.77 | ABL1 (0.59) | ABL1 | |
| SCHEMBL14097433 | 0.77 | ABL1 (0.69) | ABL1 | |
| SCHEMBL14097631 | 0.77 | ABL1 (0.69) | ABL1 | |
| SCHEMBL8997280 | 0.77 | ABL1 (0.58) | ABL1 | |
| SCHEMBL14097528 | 0.76 | ABL1 (0.68) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618974-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-17 | — | — | US | disclosed |