SCHEMBL13633607

SCHEMBL13633607

Cc1ccc(/C=C/c2ccc3c(C(=O)Oc4c(C)cc(C(=O)OCc5ccccc5)cc4C)c4ccccc4[n+](CCCCS(=O)(=O)O)c3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
TP53 P04637 2/20 0.33
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4178411 0.94 NPC1 (0.35) MAPTLMNAL3MBTL1
SCHEMBL4191631 0.94 LCK (0.34) TP53
SCHEMBL13633573 0.91 TTR (0.31) L3MBTL1
SCHEMBL4193149 0.89 NPC1 (0.35) MAPTLMNAL3MBTL1
SCHEMBL13633578 0.89 NPC1 (0.35) MAPTLMNAL3MBTL1
SCHEMBL4185433 0.87 TTR (0.35) L3MBTL1
SCHEMBL13633666 0.85
SCHEMBL7534324 0.85 MAPT (0.33) MAPTTP53LMNAL3MBTL1
SCHEMBL5663898 0.84 NPC1 (0.35) MAPTTP53L3MBTL1
SCHEMBL4187542 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611909-B1 Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-11-03 US disclosed