Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 14/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 3/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922997 | 0.90 | P2RY12 (0.48) | P2RY12FBP1MEN1PABPC1KMT2A | |
| SCHEMBL9922690 | 0.86 | P2RY12 (0.46) | P2RY12FBP1MEN1PABPC1KMT2A | |
| SCHEMBL13633801 | 0.86 | P2RY12 (0.47) | P2RY12FBP1MEN1KMT2AMAPT | |
| SCHEMBL9920086 | 0.82 | P2RY12 (0.54) | P2RY12FBP1MEN1KMT2AMAPT | |
| SCHEMBL9922994 | 0.81 | P2RY12 (0.43) | P2RY12FBP1MEN1PABPC1KMT2A | |
| SCHEMBL9922990 | 0.81 | P2RY12 (0.51) | P2RY12FBP1MEN1PABPC1KMT2A | |
| SCHEMBL9922112 | 0.80 | P2RY12 (0.53) | P2RY12FBP1MEN1KMT2AMAPT | |
| SCHEMBL9922730 | 0.80 | P2RY12 (0.48) | P2RY12FBP1MEN1KMT2AMAPT | |
| SCHEMBL9922993 | 0.80 | P2RY12 (0.48) | P2RY12FBP1MEN1KMT2AMAPT | |
| SCHEMBL9922996 | 0.80 | P2RY12 (0.44) | P2RY12FBP1MEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |