Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.58 |
| ▸ | FBP1 | P09467 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922330 | 0.92 | P2RY12 (0.62) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL9922321 | 0.92 | P2RY12 (0.57) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL9922101 | 0.90 | P2RY12 (0.56) | P2RY12FBP1KMT2AMEN1LMNA | |
| SCHEMBL9922322 | 0.90 | P2RY12 (0.56) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL9922092 | 0.90 | P2RY12 (0.56) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL9923145 | 0.88 | P2RY12 (0.56) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL1548643 | 0.88 | P2RY12 (0.55) | P2RY12FBP1KMT2AMEN1HTT | |
| SCHEMBL9922859 | 0.88 | P2RY12 (0.55) | P2RY12FBP1KMT2AMEN1KIT | |
| SCHEMBL9922093 | 0.87 | P2RY12 (0.53) | P2RY12FBP1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9922672 | 0.87 | P2RY12 (0.56) | P2RY12FBP1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |