Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 7/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | GSAP | A4D1B5 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922944 | 0.90 | P2RY12 (0.42) | P2RY12GCKFBP1CHRM5SLC22A12 | |
| SCHEMBL9922548 | 0.88 | P2RY12 (0.41) | P2RY12FBP1EGFRMETPSEN1 | |
| SCHEMBL9922555 | 0.88 | P2RY12 (0.40) | P2RY12EGFRMETPSEN1PSEN2 | |
| SCHEMBL9922946 | 0.87 | P2RY12 (0.46) | P2RY12FBP1METPSEN1PSEN2 | |
| SCHEMBL9923178 | 0.87 | P2RY12 (0.43) | P2RY12FBP1EGFRMETPSEN1 | |
| SCHEMBL12161337 | 0.87 | P2RY12 (0.43) | P2RY12FBP1METCHRM5APP | |
| SCHEMBL9923188 | 0.86 | P2RY12 (0.46) | P2RY12FBP1METCHRM5PSEN1 | |
| SCHEMBL9923191 | 0.86 | P2RY12 (0.43) | P2RY12FBP1EGFRMETPSEN1 | |
| SCHEMBL9923184 | 0.86 | P2RY12 (0.44) | P2RY12FBP1CHRM5SLC22A12GSAP | |
| SCHEMBL12161343 | 0.85 | P2RY12 (0.44) | P2RY12FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |