⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524637 | 0.79 | CCNE2 (0.32) | — | |
| SCHEMBL10278370 | 0.75 | DAGLA (0.30) | — | |
| SCHEMBL12126034 | 0.74 | — | — | |
| SCHEMBL3436268 | 0.74 | SLC6A2 (0.39) | — | |
| SCHEMBL13827902 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL19375355 | 0.72 | — | — | |
| SCHEMBL3436247 | 0.72 | SLC6A2 (0.50) | — | |
| SCHEMBL24524601 | 0.71 | ACACB (0.33) | — | |
| SCHEMBL16945634 | 0.71 | SLC6A2 (0.33) | — | |
| SCHEMBL7071890 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |