Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162579 | 1.00 | HRH3 (0.47) | HRH3PTGER1SCDLDHAOGA | |
| SCHEMBL3554282 | 0.92 | HRH3 (0.44) | HRH3PTGER1SCDLDHAOGA | |
| SCHEMBL3435877 | 0.92 | HRH3 (0.52) | HRH3PTGER1SCDLDHAOGA | |
| SCHEMBL2770634 | 0.89 | PTGER1 (0.41) | HRH3PTGER1LDHAOGASMN1; SMN2 | |
| SCHEMBL13161921 | 0.88 | HRH3 (0.60) | HRH3SCDPIN1RAB9ASMN1; SMN2 | |
| SCHEMBL13163986 | 0.86 | HRH3 (0.43) | HRH3PTGER1SCDLDHAOGA | |
| SCHEMBL13270613 | 0.86 | HRH3 (0.45) | HRH3PTGER1SCDPIN1RAB9A | |
| SCHEMBL15888538 | 0.84 | HRH3 (0.48) | HRH3OGARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13162807 | 0.82 | HRH3 (0.48) | HRH3PTGER1SCDLDHAOGA | |
| SCHEMBL2079085 | 0.82 | HRH3 (0.54) | HRH3PTGER1SCDLDHAOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |