Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634564 | 0.94 | SCD (0.35) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13634566 | 0.94 | SCD (0.35) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13638921 | 0.93 | KMT2A (0.36) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13638893 | 0.93 | KMT2A (0.36) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13634846 | 0.92 | IRAK4 (0.37) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13634847 | 0.92 | IRAK4 (0.37) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13270650 | 0.89 | MAPT (0.39) | SCDSCD5IRAK4KMT2AS1PR1 | |
| SCHEMBL13638996 | 0.89 | SCD (0.35) | SCDSCD5IRAK4KMT2AOPRK1 | |
| SCHEMBL13634557 | 0.88 | S1PR1 (0.42) | SCDSCD5S1PR1CNR2 | |
| SCHEMBL13634750 | 0.86 | IRAK4 (0.38) | SCDSCD5IRAK4KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |