Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.32 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164103 | 0.94 | ACKR3 (0.36) | KMT2AGRM2MCHR1KCNH2SCD | |
| SCHEMBL13634766 | 0.92 | KMT2A (0.41) | KMT2AKCNH2OPRK1 | |
| SCHEMBL13164112 | 0.90 | GRM2 (0.37) | KMT2AGRM2MCHR1KCNH2SCD | |
| SCHEMBL13639001 | 0.89 | KMT2A (0.38) | KMT2AGRM2KCNH2SCDSCD5 | |
| SCHEMBL2770243 | 0.89 | KMT2A (0.38) | KMT2AGRM2KCNH2SCDSCD5 | |
| SCHEMBL13634657 | 0.89 | DRD4 (0.41) | KMT2AGRM2MCHR1KCNH2SCD | |
| SCHEMBL13634656 | 0.89 | DRD4 (0.41) | KMT2AGRM2MCHR1KCNH2SCD | |
| SCHEMBL13164111 | 0.87 | MCHR1 (0.38) | KMT2AGRM2MCHR1KCNH2OPRK1 | |
| SCHEMBL13162737 | 0.87 | GRM2 (0.36) | KMT2AGRM2MCHR1KCNH2SCD | |
| SCHEMBL13634734 | 0.87 | KMT2A (0.41) | KMT2AKCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |