⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135613 | 0.90 | — | — | |
| SCHEMBL133879 | 0.88 | BRD4 (0.46) | — | |
| SCHEMBL99664 | 0.83 | — | — | |
| SCHEMBL3477989 | 0.83 | KMT2A (0.58) | — | |
| SCHEMBL135643 | 0.82 | — | — | |
| SCHEMBL99046 | 0.81 | — | — | |
| SCHEMBL136346 | 0.79 | KMT2A (0.51) | — | |
| SCHEMBL15875823 | 0.79 | KMT2A (0.73) | — | |
| SCHEMBL3475417 | 0.73 | — | — | |
| SCHEMBL136345 | 0.73 | KMT2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430029-A1 | THIENO [2, 3-B]PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | Katholieke Universiteit Leuven (BE) | 2012-03-21 | — | — | EP | disclosed |
| US-20120059028-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-03-08 | — | — | US | disclosed |