Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127604 | 0.96 | IRAK4 (0.36) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13634556 | 0.94 | IRAK4 (0.37) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL2771848 | 0.94 | IRAK4 (0.37) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13638945 | 0.93 | IRAK4 (0.36) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13634733 | 0.93 | IRAK4 (0.36) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13634554 | 0.93 | IRAK4 (0.38) | IRAK4JAK2JAK1KMT2ASCD | |
| Fumaric Acid SCHEMBL2774883 | 0.93 | IRAK4 (0.34) | IRAK4JAK2JAK1KMT2ASCD | |
| Fumaric Acid SCHEMBL2774886 | 0.93 | IRAK4 (0.34) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13638892 | 0.92 | IRAK4 (0.36) | IRAK4JAK2JAK1KMT2ASCD | |
| SCHEMBL13634756 | 0.91 | IRAK4 (0.38) | IRAK4JAK2JAK1KMT2ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |