Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635083 | 0.94 | P2RY12 (0.66) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635164 | 0.94 | P2RY12 (0.67) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635262 | 0.91 | P2RY12 (0.64) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635114 | 0.91 | P2RY12 (0.66) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635072 | 0.91 | P2RY12 (0.64) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635618 | 0.90 | P2RY12 (0.68) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13634834 | 0.89 | P2RY12 (0.62) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635281 | 0.89 | P2RY12 (0.68) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635048 | 0.89 | P2RY12 (0.64) | P2RY12MAPTTP53RXFP1SMN1; SMN2 | |
| SCHEMBL13635117 | 0.89 | P2RY12 (0.62) | P2RY12MAPTTP53RXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |