Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.43 |
| ▸ | DNM1L | O00429 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634936 | 0.88 | IRAK4 (0.41) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13270719 | 0.88 | IRAK4 (0.41) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13270709 | 0.87 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13634539 | 0.87 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13634520 | 0.86 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13638781 | 0.86 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13634605 | 0.85 | PIM1 (0.40) | IRAK4DNM1LPIM1JAK2JAK1 | |
| SCHEMBL13634842 | 0.84 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL2769203 | 0.83 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 | |
| SCHEMBL13634904 | 0.83 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |