SCHEMBL13635194

SCHEMBL13635194

CC(C)(C)OC(=O)C(C)(C)OC[C@H]1CCC[C@@H](F)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.32
NR1H2 P55055 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928444 0.84 CHRM2 (0.36) BTKNR1H2
SCHEMBL1928441 0.84 CHRM2 (0.36) BTKNR1H2
SCHEMBL4485705 0.84 NR1H2 (0.39) BTKNR1H2
SCHEMBL1929339 0.84 CHRM2 (0.36) BTKNR1H2
SCHEMBL4377241 0.84 NR1H2 (0.39) BTKNR1H2
SCHEMBL4382601 0.84 NR1H2 (0.39) BTKNR1H2
SCHEMBL4918281 0.84 NR1H2 (0.39) BTKNR1H2
SCHEMBL4478623 0.84 NR1H2 (0.39) BTKNR1H2
SCHEMBL1928447 0.84 CHRM2 (0.36) BTKNR1H2
Alcohol SCHEMBL4926025 0.81 CHRM2 (0.33) BTKNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1789402-B1 2-{-3-2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY };-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES SANOFI AVENTIS DEUTSCHLAND (DE) 2009-11-18 EP disclosed