Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635072 | 0.94 | P2RY12 (0.64) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635048 | 0.94 | P2RY12 (0.64) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635059 | 0.93 | P2RY12 (0.61) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635056 | 0.93 | P2RY12 (0.61) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635262 | 0.92 | P2RY12 (0.64) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635057 | 0.92 | P2RY12 (0.64) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635114 | 0.92 | P2RY12 (0.66) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635117 | 0.92 | P2RY12 (0.62) | P2RY12TP53MAPTRXFP1KMT2A | |
| SCHEMBL13635077 | 0.92 | P2RY12 (0.64) | P2RY12TP53MAPTRXFP1GAA | |
| SCHEMBL13634932 | 0.92 | P2RY12 (0.63) | P2RY12TP53MAPTRXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |