Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376625 | 0.92 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4378758 | 0.83 | MAPK14 (0.79) | MAPK14 | |
| SCHEMBL4377189 | 0.83 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4378496 | 0.81 | MAPK14 (0.75) | MAPK14 | |
| SCHEMBL4376201 | 0.77 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL4381263 | 0.74 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL4377489 | 0.74 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4379694 | 0.73 | MAPK14 (0.80) | MAPK14 | |
| SCHEMBL4378510 | 0.71 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL3521380 | 0.71 | MAPK14 (0.64) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |