Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.62 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376946 | 0.93 | MAPK14 (0.62) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4378632 | 0.91 | MAPK14 (0.59) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4384623 | 0.89 | MAPK14 (0.64) | MAPK14MAPKAPK2 | |
| SCHEMBL4384930 | 0.88 | MAPK14 (0.61) | MAPK14MAPKAPK2 | |
| SCHEMBL4384545 | 0.87 | MAPK14 (0.58) | MAPK14MAPKAPK2 | |
| SCHEMBL4380173 | 0.85 | MAPK14 (0.54) | MAPK14MAPKAPK2 | |
| SCHEMBL4387471 | 0.85 | MAPK14 (0.58) | MAPK14MAPKAPK2 | |
| SCHEMBL29593809 | 0.85 | MAPK14 (0.58) | MAPK14MAPKAPK2 | |
| SCHEMBL4376131 | 0.82 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL4384555 | 0.81 | MAPK14 (0.61) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |