Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.61 |
| ▸ | GCK | P35557 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922645 | 0.96 | P2RY12 (0.64) | P2RY12GCKHTR3APSEN1PSEN2 | |
| SCHEMBL9922564 | 0.87 | P2RY12 (0.69) | P2RY12GAAKMT2AALDH1A1HTT | |
| SCHEMBL9922508 | 0.87 | P2RY12 (0.63) | P2RY12HTR3APSEN1PSEN2APH1B | |
| SCHEMBL9923147 | 0.87 | P2RY12 (0.54) | P2RY12GCKPSEN1PSEN2APH1B | |
| SCHEMBL13635110 | 0.86 | P2RY12 (0.66) | P2RY12HTR3AGAAKMT2AHTT | |
| SCHEMBL9922558 | 0.86 | P2RY12 (0.66) | P2RY12PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9922861 | 0.86 | P2RY12 (0.51) | P2RY12GCKPSEN1PSEN2APH1B | |
| SCHEMBL9922461 | 0.86 | P2RY12 (0.64) | P2RY12HTR3APSEN1PSEN2APH1B | |
| SCHEMBL9922499 | 0.85 | P2RY12 (0.70) | P2RY12HTR3AGAAKMT2AHTT | |
| SCHEMBL9922505 | 0.85 | P2RY12 (0.58) | P2RY12GCKPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |