Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.69 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374694 | 0.90 | PTPN1 (0.85) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3729135 | 0.84 | PTPN1 (0.76) | PTPN1 | |
| SCHEMBL4374325 | 0.84 | PTPN1 (0.81) | PTPN1 | |
| SCHEMBL13040908 | 0.82 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL4382293 | 0.82 | PTPN1 (0.75) | PTPN1NLRP3 | |
| SCHEMBL4371507 | 0.81 | PTPN1 (0.78) | PTPN1NLRP3 | |
| SCHEMBL3732057 | 0.81 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL4381209 | 0.81 | PTPN1 (0.82) | PTPN1 | |
| SCHEMBL4376458 | 0.80 | PTPN1 (0.81) | PTPN1 | |
| SCHEMBL4374723 | 0.80 | PTPN1 (1.00) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | disclosed |