SCHEMBL13636207

SCHEMBL13636207

C/C=C(\CCC(=O)c1ccc(C(F)(F)F)cc1)N1CCN(C(CC)CC)CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 19/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378029 0.87 HRH3 (1.00) HRH3
Hydrochloric Acid SCHEMBL4379272 0.86 HRH3 (1.00) HRH3
SCHEMBL4379406 0.76 HRH3 (1.00) HRH3
Hydrochloric Acid SCHEMBL4375912 0.75 HRH3 (1.00) HRH3
SCHEMBL4388880 0.73 HRH3 (1.00) HRH3
SCHEMBL4386127 0.73 HRH3 (1.00) HRH3
SCHEMBL4375727 0.73 HRH3 (1.00) HRH3
Hydrochloric Acid SCHEMBL4383019 0.72 HRH3 (1.00) HRH3
Hydrochloric Acid SCHEMBL4381864 0.72 HRH3 (1.00) HRH3
Hydrochloric Acid SCHEMBL4378887 0.72 HRH3 (1.00) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1421071-B1 SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS HIGH POINT PHARMACEUTICALS LLC (US) 2009-11-18 EP disclosed