Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745217 | 0.92 | PTPN1 (1.00) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| SCHEMBL3734469 | 0.85 | PTPN1 (1.00) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| SCHEMBL4379518 | 0.83 | PTPN1 (1.00) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| SCHEMBL13040885 | 0.83 | PTPN1 (1.00) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| Trifluoroacetic Acid SCHEMBL3737206 | 0.81 | PTPN1 (0.94) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| SCHEMBL4377769 | 0.80 | PTPN1 (0.55) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3732511 | 0.80 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL3732083 | 0.78 | PTPN1 (0.78) | PTPN1CYP1A2CYP2C19 | |
| SCHEMBL3737209 | 0.78 | PTPN1 (0.76) | PTPN1CYP1A2CYP2D6CYP2C19RECQL | |
| Trifluoroacetic Acid SCHEMBL3734734 | 0.78 | PTPN1 (0.89) | PTPN1CYP1A2CYP2D6CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | disclosed |