Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 8/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471550 | 0.88 | KMT2A (0.46) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12060911 | 0.87 | IDO1 (0.47) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16496996 | 0.87 | IDO1 (0.46) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3814131 | 0.87 | IDO1 (0.46) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1589942 | 0.87 | SCD (0.45) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29624718 | 0.87 | IDO1 (0.46) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3814137 | 0.87 | IDO1 (0.46) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12265488 | 0.87 | KDM4E (0.45) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1589943 | 0.87 | SCD (0.45) | GPR119KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4267298 | 0.86 | ACACB (0.59) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |