Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13339965 | 0.83 | KDM4E (0.40) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4388135 | 0.83 | MAPT (0.35) | MAPTALDH1A1 | |
| SCHEMBL13339864 | 0.83 | PARP10 (0.35) | MEN1KMT2A | |
| SCHEMBL13339934 | 0.83 | VHL (0.44) | MEN1MAPTKMT2ATDP1GAA | |
| Hydrochloric Acid SCHEMBL3495210 | 0.82 | PARP10 (0.34) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3491868 | 0.82 | VHL (0.43) | MEN1MAPTKMT2ATDP1GAA | |
| Hydrochloric Acid SCHEMBL3494767 | 0.82 | MAPT (0.34) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3494673 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1 | |
| SCHEMBL13339874 | 0.81 | HTR2A (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3493376 | 0.80 | HTR2A (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |