Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.49 |
| ▸ | ACACA | Q13085 | 16/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494625 | 0.90 | ACACB (0.47) | ACACBACACAALDH1A1HPGD | |
| SCHEMBL3495519 | 0.85 | ACACB (0.47) | ACACBACACAALDH1A1HPGD | |
| SCHEMBL3493127 | 0.82 | ACACB (0.66) | ACACBACACA | |
| SCHEMBL13636597 | 0.78 | ACACB (0.45) | ACACBACACAALDH1A1HPGDKDM4E | |
| SCHEMBL3497401 | 0.78 | ACACB (0.79) | ACACBACACA | |
| SCHEMBL3495363 | 0.77 | ACACB (0.45) | ACACBACACAALDH1A1HPGDKDM4E | |
| SCHEMBL2212213 | 0.75 | TP53 (0.51) | ACACBACACAALDH1A1HPGDKDM4E | |
| SCHEMBL13969593 | 0.74 | HPGD (0.54) | ACACBALDH1A1HPGDKDM4EGAA | |
| SCHEMBL3492059 | 0.74 | EPHX2 (0.48) | ACACB | |
| SCHEMBL3491661 | 0.74 | ACACB (0.44) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |