SCHEMBL13636656

SCHEMBL13636656

CCCc1ccc(C(F)(F)Oc2cc(F)c(-c3cc(F)c(C(F)(F)F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CNR2 P34972 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7732825 0.92 TAAR1 (0.37) MAOBTAAR1THRB
SCHEMBL15744364 0.91
SCHEMBL13002202 0.90 RARB (0.33) MAOBCNR2THRB
SCHEMBL7735261 0.90 MAOB (0.36) MAOBTAAR1THRB
SCHEMBL15745194 0.89 MAOB (0.32) MAOB
SCHEMBL7731652 0.88 MAOB (0.39) MAOBTAAR1THRB
SCHEMBL18719622 0.87 MAOB (0.34) MAOB
SCHEMBL18747817 0.86 RARB (0.35) THRB
SCHEMBL17365750 0.86 S1PR1 (0.33) MAOBTAAR1
SCHEMBL12976806 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123623-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2009-11-25 EP disclosed