Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.47 |
| ▸ | ACACA | Q13085 | 18/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3492811 | 0.81 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3492814 | 0.81 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL2210681 | 0.75 | ACACB (0.60) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL12510672 | 0.72 | ACACB (0.58) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL3492029 | 0.72 | ACACB (0.58) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL3491416 | 0.71 | ACACB (0.60) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL12432101 | 0.71 | ACACB (0.56) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL12432136 | 0.71 | ACACB (0.56) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL3492643 | 0.71 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3492645 | 0.71 | ACACB (0.48) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |