Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.42 |
| ▸ | GABRE | P78334 | 3/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068070 | 0.74 | CCR1 (0.40) | KDM4EKMT2AHPGDPARP1TDP1 | |
| SCHEMBL1664968 | 0.71 | KDM4C (0.46) | KDM4EKMT2AKDM6BKDM4AKDM4D | |
| SCHEMBL29507247 | 0.71 | KDM4C (0.46) | KDM4EKMT2AKDM6BKDM4AKDM4D | |
| SCHEMBL10111018 | 0.71 | KDM4E (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1082037 | 0.71 | AXL (0.47) | NOTUMCAMKK2 | |
| SCHEMBL13201391 | 0.71 | MEN1 (0.36) | KMT2AHPGDPARP1ALDH1A1PDPK1 | |
| SCHEMBL3147727 | 0.71 | DAO (0.44) | KMT2APARP1PDPK1MEN1 | |
| SCHEMBL2314618 | 0.69 | HSD17B10 (0.46) | KDM4EPARP1TDP1ALDH1A1NOTUM | |
| SCHEMBL2079039 | 0.69 | MEN1 (0.32) | KDM4EKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL27473136 | 0.69 | GABRR1 (0.35) | KDM4EKMT2AHPGDPARP1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123651-A1 | CONDENSED PYRIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-25 | — | — | EP | disclosed |