Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13441807 | 0.89 | PTGDR2 (0.58) | PTGDR2CYP2C9PPARGPPARDFFAR1 | |
| SCHEMBL13441809 | 0.89 | PTGDR2 (0.69) | PTGDR2CYP2C9PPARGPPARDFFAR1 | |
| SCHEMBL13637156 | 0.84 | PTGDR2 (0.69) | PTGDR2CYP2C9FFAR1 | |
| SCHEMBL13441825 | 0.82 | PTGDR2 (0.79) | PTGDR2CYP2C9 | |
| SCHEMBL1368182 | 0.81 | PTGDR2 (1.00) | PTGDR2CYP2C9 | |
| SCHEMBL13637155 | 0.80 | PTGDR2 (0.61) | PTGDR2CYP2C9PPARGPPARDFFAR1 | |
| SCHEMBL13441626 | 0.79 | FFAR1 (0.50) | PTGDR2CYP2C9PPARGPPARDFFAR1 | |
| SCHEMBL3711608 | 0.76 | PTGDR2 (0.85) | PTGDR2CYP2C9 | |
| SCHEMBL3578823 | 0.74 | PTGDR2 (0.65) | PTGDR2CYP2C9FFAR1 | |
| SCHEMBL1368495 | 0.74 | PTGDR2 (1.00) | PTGDR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622491-B2 | Type 2 diabetes, atherosclerosis, cardiovascular disease, Syndrome X; carboxylic acids with dialkyldiether or thioether linking groups e.g. {4-[3-(2-Benzotriazol-2-yl-4-chloro-phenoxy)-propoxy]-phenyl}-acetic acid and {4-[3-(2-benzotriazol-2-yl-4-thiophen-2-yl-phenoxy)-propoxy]-phenyl}-acetic acid | METABOLEX INC. (US) | 2009-11-24 | — | — | US | disclosed |