Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA4 | P22748 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 16/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420292 | 0.87 | PTGER2 (0.52) | CA12CA1CA2CA4CA9 | |
| SCHEMBL4945973 | 0.86 | CA12 (0.58) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13398723 | 0.85 | PTGER2 (0.54) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5046357 | 0.84 | CA12 (0.57) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13398734 | 0.83 | PTGER2 (0.54) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5048075 | 0.82 | PTGER2 (0.54) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13399398 | 0.80 | PTGER2 (0.58) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL5047950 | 0.80 | CA12 (0.77) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13399069 | 0.80 | PTGER2 (0.67) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13399315 | 0.79 | PTGER2 (0.57) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622475-B2 | EP2 agonists | PFIZER INC (US) | 2009-11-24 | — | — | US | disclosed |