Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 16/20 | 0.78 |
| ▸ | PDE1B | Q01064 | 16/20 | 0.78 |
| ▸ | PDE1C | Q14123 | 16/20 | 0.78 |
| ▸ | ESR1 | P03372 | 5/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652566 | 0.91 | PDE1A (0.77) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8656908 | 0.91 | PDE1A (0.77) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8654839 | 0.91 | PDE1A (0.77) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8768184 | 0.90 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8768178 | 0.90 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8768173 | 0.90 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8767710 | 0.88 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8767689 | 0.88 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8767701 | 0.88 | PDE1A (0.76) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL8767678 | 0.86 | PDE1A (1.00) | PDE1APDE1BPDE1CESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196163-B1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INSULIN RESISTANCE | ENDORECH INC (CA) | 2009-11-11 | — | — | EP | disclosed |