Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227825 | 0.84 | ESR1 (0.48) | ESR1ESR2 | |
| SCHEMBL227757 | 0.81 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL228130 | 0.81 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL226874 | 0.81 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL228420 | 0.81 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL227923 | 0.80 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL229287 | 0.80 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL227944 | 0.80 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL226959 | 0.79 | ESR1 (0.45) | ESR1ESR2 | |
| SCHEMBL228507 | 0.78 | ESR1 (0.54) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612114-B2 | Such as (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino }-4-methoxyphenyl }-5,6,7,8-tetrahydronaphthalen-2-ol; osteoporosis; breast cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |