Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637621 | 1.00 | TACR1 (0.77) | TACR1CYP3A4CYP2D6CYP2C9SIGMAR1 | |
| SCHEMBL13627744 | 0.88 | TACR1 (0.76) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3162954 | 0.88 | TACR1 (0.76) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13451384 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL13627557 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL5495988 | 0.87 | TACR1 (0.83) | TACR1 | |
| SCHEMBL13451657 | 0.87 | TACR1 (0.83) | TACR1 | |
| SCHEMBL3163349 | 0.87 | TACR1 (0.83) | TACR1 | |
| SCHEMBL13627558 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL5499015 | 0.87 | TACR1 (0.83) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |