SCHEMBL13637813

SCHEMBL13637813

CCC/C=C/NC(=O)/C=C\C=C/C=C\CCCC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.52
CNR1 P21554 6/20 0.52
FAAH O00519 2/20 0.47
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
FASN P49327 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376254 0.89 CNR1 (0.66) CNR2CNR1FAAHKDM4ECYP3A4
SCHEMBL5155217 0.78 CNR1 (0.51) CNR2CNR1FAAHCYP3A4MAPT
SCHEMBL11158608 0.77 PPARA (0.56) CNR2CNR1KDM4EALDH1A1TSHR
SCHEMBL30063539 0.77 PPARA (0.56) CNR2CNR1KDM4EALDH1A1TSHR
SCHEMBL11158612 0.77 PPARA (0.56) CNR2CNR1KDM4EALDH1A1TSHR
SCHEMBL11158609 0.77 PPARA (0.56) CNR2CNR1KDM4EALDH1A1TSHR
SCHEMBL29578136 0.76 CNR2 (0.62) CNR2CNR1FAAHKDM4EFASN
SCHEMBL9580042 0.75 PTPN1 (0.50) CNR2CNR1FAAHMAPTCYP2C9
SCHEMBL9580029 0.75 PTPN1 (0.50) CNR2CNR1FAAHMAPTCYP2C9
SCHEMBL11155795 0.75 PPARA (0.58) CNR2CNR1KDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112135-B1 E2, E4,Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same INT FLAVORS & FRAGRANCES INC (US) 2013-06-19 EP disclosed
EP-1496042-B1 E2, E4,Z8-Undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same INT FLAVORS & FRAGRANCES INC (US) 2009-11-11 EP disclosed
EP-2112135-A2 E2, E4,Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2009-10-28 EP disclosed