Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923271 | 0.93 | P2RY12 (0.43) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13638637 | 0.87 | P2RY12 (0.36) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13638640 | 0.83 | P2RY12 (0.38) | P2RY12MEN1KMT2ABTKBRD4 | |
| SCHEMBL12177675 | 0.82 | P2RY12 (0.41) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9922303 | 0.82 | P2RY12 (0.46) | P2RY12FBP1MEN1KMT2ACSF1R | |
| SCHEMBL14228651 | 0.82 | P2RY12 (0.39) | P2RY12FBP1MEN1TP53KMT2A | |
| SCHEMBL14228581 | 0.82 | P2RY12 (0.42) | P2RY12FBP1MEN1KMT2ABTK | |
| SCHEMBL9923273 | 0.82 | P2RY12 (0.43) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12177095 | 0.81 | P2RY12 (0.34) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12177246 | 0.80 | PIK3CA (0.34) | P2RY12FBP1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |