⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074443 | 0.87 | — | — | |
| SCHEMBL4074287 | 0.78 | — | — | |
| SCHEMBL4075199 | 0.77 | USP30 (0.43) | — | |
| SCHEMBL4072771 | 0.75 | MAPK1 (0.49) | — | |
| SCHEMBL4075222 | 0.75 | — | — | |
| SCHEMBL4079434 | 0.73 | — | — | |
| SCHEMBL4072807 | 0.72 | — | — | |
| SCHEMBL4076024 | 0.71 | — | — | |
| SCHEMBL4074418 | 0.71 | MAP3K5 (0.46) | — | |
| SCHEMBL4080052 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275577-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | PFIZER INC | 2009-11-05 | — | — | US | disclosed |
| US-7563788-B2 | Substituted Imidazo[1,2-a]pyridines as Antibacterial Agents | PFIZER INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20070191394-A1 | Antibacterial agents | WARNER-LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |