Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922948 | 0.93 | P2RY12 (0.54) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL9922362 | 0.91 | P2RY12 (0.54) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL12161443 | 0.91 | P2RY12 (0.52) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL12161436 | 0.90 | P2RY12 (0.53) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL12161445 | 0.89 | P2RY12 (0.51) | P2RY12NOD1TP53PPARG | |
| SCHEMBL9922949 | 0.89 | P2RY12 (0.51) | P2RY12NOD1TP53PPARG | |
| SCHEMBL9922941 | 0.89 | P2RY12 (0.60) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL9922938 | 0.88 | P2RY12 (0.57) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL9922577 | 0.88 | P2RY12 (0.51) | P2RY12NOD1TP53PPARGFBP1 | |
| SCHEMBL9922952 | 0.88 | P2RY12 (0.49) | P2RY12NOD1TP53PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |