Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SCN2B | O60939 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160810 | 0.91 | P2RY12 (0.53) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL9922465 | 0.91 | P2RY12 (0.53) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL9922468 | 0.90 | P2RY12 (0.51) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL12160800 | 0.90 | P2RY12 (0.51) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL12177239 | 0.90 | P2RY12 (0.51) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL9922470 | 0.89 | P2RY12 (0.51) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL12160803 | 0.89 | P2RY12 (0.53) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL12177070 | 0.89 | P2RY12 (0.48) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL9922787 | 0.88 | P2RY12 (0.50) | P2RY12MAPTFBP1LMNASMN1; SMN2 | |
| SCHEMBL9922471 | 0.88 | P2RY12 (0.50) | P2RY12MAPTFBP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |