Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923172 | 0.93 | P2RY12 (0.62) | P2RY12ERCC1FEN1ERCC4KIT | |
| SCHEMBL9922541 | 0.90 | P2RY12 (0.52) | P2RY12ERCC1FEN1ERCC4FBP1 | |
| SCHEMBL9922446 | 0.89 | P2RY12 (0.53) | P2RY12ERCC1FEN1ERCC4KIT | |
| SCHEMBL14228361 | 0.89 | P2RY12 (0.53) | P2RY12ERCC1FEN1ERCC4CREBBP | |
| SCHEMBL12161655 | 0.88 | P2RY12 (0.54) | P2RY12ERCC1FEN1ERCC4KIT | |
| SCHEMBL9922989 | 0.88 | P2RY12 (0.48) | P2RY12ERCC1FEN1ERCC4BRD4 | |
| SCHEMBL12177346 | 0.87 | P2RY12 (0.46) | P2RY12ERCC1FEN1ERCC4KIT | |
| SCHEMBL9923019 | 0.86 | P2RY12 (0.65) | P2RY12ERCC1FEN1ERCC4BRD4 | |
| SCHEMBL12177347 | 0.84 | P2RY12 (0.54) | P2RY12ERCC1FEN1ERCC4KIT | |
| SCHEMBL9922330 | 0.84 | P2RY12 (0.62) | P2RY12ERCC1FEN1ERCC4KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |