Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565573 | 0.82 | HDAC8 (0.63) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL3569375 | 0.82 | HDAC8 (0.63) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL13163933 | 0.81 | HDAC8 (0.59) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL13479179 | 0.81 | HDAC8 (0.64) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL20873715 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL20873716 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL13163127 | 0.80 | HDAC8 (0.57) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL1241999 | 0.80 | HDAC8 (0.67) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL1241170 | 0.80 | HDAC8 (0.67) | HDAC8HDAC6HDAC1CRHBPCRHR2 | |
| SCHEMBL1241175 | 0.80 | HDAC8 (0.67) | HDAC8HDAC6HDAC1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |