Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638765 | 0.95 | MCHR1 (0.37) | MCHR1PARP1TNK1PDCD1CD274 | |
| SCHEMBL13638994 | 0.94 | MCHR1 (0.37) | MCHR1PARP1TNK1UTS2RGPR6 | |
| SCHEMBL13634612 | 0.93 | MCHR1 (0.38) | MCHR1PARP1TNK1UTS2RGPR6 | |
| SCHEMBL13638933 | 0.93 | MCHR1 (0.39) | MCHR1PARP1TNK1UTS2RKMT2A | |
| SCHEMBL13638886 | 0.92 | MCHR1 (0.38) | MCHR1PARP1TNK1UTS2RKMT2A | |
| SCHEMBL13638822 | 0.92 | MCHR1 (0.38) | MCHR1PARP1TNK1UTS2RKMT2A | |
| SCHEMBL13638909 | 0.92 | MCHR1 (0.38) | MCHR1PARP1TNK1UTS2RGPR6 | |
| SCHEMBL13634805 | 0.92 | MCHR1 (0.38) | MCHR1PARP1TNK1UTS2RGPR6 | |
| SCHEMBL13634684 | 0.92 | MCHR1 (0.39) | MCHR1PARP1TNK1UTS2R | |
| SCHEMBL13638826 | 0.92 | MCHR1 (0.40) | MCHR1PARP1TNK1UTS2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |