Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639165 | 0.98 | KCNA3 (0.59) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL13918233 | 0.94 | KCNA3 (0.58) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL28132684 | 0.88 | KCNA3 (0.54) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL17138206 | 0.87 | TSHR (0.45) | KCNA3ALDH1A1 | |
| SCHEMBL17138205 | 0.87 | TSHR (0.45) | KCNA3ALDH1A1 | |
| SCHEMBL1455117 | 0.84 | KCNA3 (0.67) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL1453581 | 0.82 | KCNA3 (0.64) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL1455375 | 0.82 | KCNA3 (0.64) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL1454537 | 0.82 | KCNA3 (0.64) | KCNA3HDAC1HDAC2LTA4HHDAC3 | |
| SCHEMBL1455068 | 0.82 | KCNA3 (0.64) | KCNA3HDAC1HDAC2LTA4HHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |