Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167525 | 1.00 | HDAC1 (0.57) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL9005287 | 0.87 | TAAR1 (0.59) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL9005286 | 0.87 | TAAR1 (0.59) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL21381119 | 0.87 | PPARA (0.68) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL19021153 | 0.87 | PPARA (0.68) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL21381118 | 0.87 | PPARA (0.68) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL21002124 | 0.85 | TAAR1 (0.69) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL13206731 | 0.84 | PPARA (0.58) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL21002162 | 0.83 | TAAR1 (0.71) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL3145532 | 0.83 | HDAC1 (0.58) | HDAC1HDAC6CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |