Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 19/20 | 0.85 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788588 | 0.92 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13639443 | 0.91 | PTGES2 (0.82) | PTGES2CA1CA2CA9 | |
| SCHEMBL3782583 | 0.85 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3770159 | 0.85 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3788581 | 0.85 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13639461 | 0.85 | PTGES2 (0.82) | PTGES2 | |
| SCHEMBL3773690 | 0.85 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3786572 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3779868 | 0.83 | CA1 (1.00) | PTGES2CA1CA2CA9 | |
| SCHEMBL3779352 | 0.81 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-B1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2009082347-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |