Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 15/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639465 | 0.91 | PTGES2 (0.67) | PTGES2GAAMAPTTSHRMAPK1 | |
| SCHEMBL13061991 | 0.86 | PTGES2 (0.88) | PTGES2 | |
| SCHEMBL3782599 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3784257 | 0.81 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782425 | 0.79 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782831 | 0.79 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3778531 | 0.77 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3777997 | 0.77 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3779732 | 0.76 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3780960 | 0.76 | PTGES2 (0.81) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-B1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2009082347-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |