Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772274 | 0.88 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3772276 | 0.88 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3776659 | 0.84 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3776655 | 0.84 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3787705 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3787710 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782849 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782844 | 0.83 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3779926 | 0.81 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3779929 | 0.81 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-B1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2012-11-07 | — | — | EP | disclosed |