Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CDC25C | P30307 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GALR1 | P47211 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174579 | 0.93 | CYP1A1 (0.54) | CDC25ACDC25BCDC25CHPGDTP53 | |
| SCHEMBL2998008 | 0.85 | HPGD (0.64) | HPGDLMNATSHR | |
| SCHEMBL5863201 | 0.84 | TP53 (0.57) | HPGDTP53POLBGALR1TDP1 | |
| SCHEMBL29617015 | 0.84 | TP53 (0.62) | HPGDTP53POLBGALR1 | |
| SCHEMBL4193217 | 0.82 | TP53 (0.61) | HPGDTP53POLBGALR1 | |
| SCHEMBL12581547 | 0.81 | NPC1 (0.56) | CDC25ACDC25BCDC25CHPGDTP53 | |
| SCHEMBL5863231 | 0.80 | TP53 (0.56) | HPGDTP53POLBGALR1LMNA | |
| SCHEMBL4114637 | 0.80 | BRAF (0.61) | CDC25BHPGDTP53POLB | |
| SCHEMBL12553322 | 0.80 | NPC1 (0.57) | CDC25BHPGDTP53POLBGALR1 | |
| SCHEMBL25014570 | 0.80 | TDP1 (0.48) | HPGDTP53POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948146-B1 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2012-11-07 | — | — | EP | disclosed |