Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.67 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.67 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.67 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.67 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.67 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.67 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.67 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.67 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.67 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171948 | 0.87 | CYP2C8 (0.69) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 | |
| SCHEMBL16400571 | 0.86 | MKNK1 (0.58) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 | |
| SCHEMBL4167549 | 0.86 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 | |
| SCHEMBL4174870 | 0.86 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 | |
| SCHEMBL3861503 | 0.84 | KAT6A (0.56) | PARP1MKNK1MKNK2PDE4DERN1 | |
| SCHEMBL12607524 | 0.82 | ERN1 (0.57) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 | |
| SCHEMBL24163691 | 0.82 | PARP1 (0.60) | PARP1ERN1FAAHCA1CA2 | |
| SCHEMBL1690557 | 0.82 | PARP1 (0.80) | PARP1PLAUPLATERN1FAAH | |
| SCHEMBL3720494 | 0.80 | PARP1 (0.67) | CYP1A2CYP3A4PARP1PLAUPLAT | |
| SCHEMBL29460667 | 0.80 | PARP1 (0.62) | CYP1A2CYP3A4CYP1A1CYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948146-B1 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2007039111-A2 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |