Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 7/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.57 |
| ▸ | CDK2 | P24941 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999780 | 0.82 | CCNE2 (0.41) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL999573 | 0.82 | CCNE2 (0.41) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL1000315 | 0.82 | CCNE2 (0.41) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL9072844 | 0.81 | CCNE1 (0.62) | CCNE2CCNE1CDK2SMN1; SMN2NPC1 | |
| SCHEMBL999845 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL999844 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL998399 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL1000757 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL998401 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 | |
| SCHEMBL1000756 | 0.77 | CCNE2 (0.39) | CCNE2CCNE1CDK2SMN1; SMN2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723128-B1 | HETEROARYL-UREAS AND THEIR USE AS GLUCOKINASE ACTIVATORS | NOVO NORDISK AS (DK) | 2012-11-07 | — | — | EP | disclosed |